• Users Online: 508
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2018  |  Volume : 15  |  Issue : 2  |  Page : 186-190

Effect of scaling and root planing on salivary alkaline phosphatase and acid phosphatase in patients with chronic periodontitis


Department of Periodontology, College of Dentistry, Hawler Medical University, Erbil, Iraq

Correspondence Address:
Chenar Anwar Mohammad
Department of Periodontology, College of Dentistry, Hawler Medical University, Erbil
Iraq
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/MJBL.MJBL_48_18

Get Permissions

Background: Chronic periodontitis affects the supporting structures of the dentition, namely, the gingiva, periodontal ligament, cementum, and alveolar bone; it arises from interactions between the host and around 700 bacterial taxa in the subgingival microbiota, and the host responses include production of different enzymes that released by stromal, epithelial, inflammatory, or bacterial cells. Objective: This study aimed to evaluate the effect of scaling and root planing on the activity level of salivary alkaline and acid phosphatase (ACP) in patients with chronic periodontitis. Materials and Methods: The study was conducted on 60 patients, 40 were with chronic periodontitis and 20 were controlled with healthy periodontium. Scaling and root planing were conducted for periodontitis patients, and saliva samples were collected at baseline before treatment and after 2, 4, and 6 weeks of periodontal therapy and from control patients to estimate the activity levels of alkaline and ACP. Results: Scaling and root planing resulted in significant reduction of plaque index, gingival index, bleeding on probing, pocket depth, and clinical attachment level after 4 weeks of treatment (P < 0.01) and also reduction of activity levels of alkaline and ACP after 2 weeks of treatment and continued into 4 weeks as compared to baseline before treatment (P < 0.01, P < 0.05). Conclusion: The activity levels of both enzymes were reduced gradually after scaling and root planing due to the reduction of inflammatory reaction and healing of periodontal tissue, so both enzymes can be used as a biomarker for periodontitis diagnosis, treatment responses, and follow-up.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed783    
    Printed59    
    Emailed0    
    PDF Downloaded92    
    Comments [Add]    

Recommend this journal