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Year : 2019  |  Volume : 16  |  Issue : 1  |  Page : 51-54

Effect of Vitamin D deficiency on pulmonary function test in a normal population

1 Department of Internal Medicine, College of Medicine, Hawler Medical University, Erbil, Iraq
2 Department of Family Medicine, Kurdistan Board for Medical Specialty (KBMS), Erbil, Iraq

Correspondence Address:
Dr. Hemin Khalid Saber
Department of Internal Medicine, College of Medicine, Hawler Medical University, Erbil
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/MJBL.MJBL_75_18

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Background: During the past years, the role of Vitamin D on wide biologic processes has received the attractiveness. Moreover, the role of Vitamin D in the prevention and treatment of respiratory infections has already been confirmed. Objective: In the present study, the pulmonary functions, including forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1) ratio, and FEV1/FVC ratio were compared between healthy individuals with and without Vitamin D deficiency. Materials and Methods: In the current case–control study, the pulmonary functions of healthy individuals with normal Vitamin D (control = 51) and with Vitamin D deficiency (cases = 57) were compared through statistical analysis. The individuals recruited in the study were screened from the outpatient clinic of medicine department of a public hospital purposively. The Vitamin D level <50 nmol/L was considered deficient. The reference values of pulmonary functions were considered as follows: FVC between 80% and 120% as normal and <80% as reduced; FEV1 ≥75 as normal and <75 as reduced; FEV1/FVC between 80% and 120% as normal. Results: The present study showed that individuals with normal level of Vitamin D (control) and those with deficient level of Vitamin D (case) were comparable in age (39.09 vs. 41.33 years; P= 0.393), and body mass index (27.48 vs. 28.39; P= 0.475), respectively. In addition, both case and control groups were similar in FVC (93.98 vs. 93.12; P= 0.653), FEV1 (90.88 vs. 89.39L; P= 0.752), and FEV1/FVC (95.94 vs. 95.01%; P= 0.777) respectively. Conclusion: The study did not show a significant difference in baseline characteristics and of those spirometry functions (FVC, FEV1, and FEV1/FVC) between the healthy individuals with normal and deficient Vitamin D levels.

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