• Users Online: 434
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2020  |  Volume : 17  |  Issue : 2  |  Page : 159-164

Seroprevalence of antinuclear antibodies, antibrucella antibodies, and hepatitis B surface antigen in women with recurrent abortion


Department of Anesthesia, Erbil Medical Technical Institute, Erbil Polytechnic University, Erbil, Iraq

Correspondence Address:
Nabaz Fisal Shakir Agha
Department of Anesthesia, Erbil Medical Technical Institute, Erbil Polytechnic University, Erbil
Iraq
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/MJBL.MJBL_96_19

Get Permissions

Background: Recurrent abortion is a globally common problem. Many factors play a crucial role in the pathogenesis of abortion such as antinuclear antibodies (ANA), antibrucella antibodies and hepatitis B surface antigen (HBsAg). Objectives: The study objective was to estimate the serum levels of antinuclear antibodies (ANAs), antibrucella antibodies, and hepatitis B surface antigen among recurrent aborting women. Materials and Methods: One hundred and twenty women were enrolled in this prospective case–controlled study from Maternity Hospital, Erbil City, Iraq. The study included sixty patients with a history of three and more attacks of previous abortions and sixty healthy pregnant women. All were screened for ANA-IgG, antibrucella antibodies, and hepatitis B surface antigen (HBsAg) in serum. Results: It was noted that 15/60 (25%) patients and 6/60 (10%) healthy controls were positive for ANA-IgG with a mean concentration of 6.2 ± 0.4 IU/ml in the patient group and 0.75 ± 0.325 IU/ml in the healthy controls with statistical significance at P ≤ 0.05. The distribution for ANA with antibrucella and HbsAg in patient group was as follows: 12/15 (80%) and 6/15 (46.15%), respectively, among the seropositive ANA patients with a high significance atP < 0.01 for antibrucella and a significance atP < 0.05 for HbsAg. Conclusions: ANAs constitute an important cause of recurrent mid-trimester abortion in women. Furthermore, there is growing clues of the pathogenicity of Brucella organisms and hepatitis B virus, especially as agents of adverse pregnancy.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed54    
    Printed0    
    Emailed0    
    PDF Downloaded8    
    Comments [Add]    

Recommend this journal