Medical Journal of Babylon

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 15  |  Issue : 1  |  Page : 21--24

The role of autonomic neuropathy in predicting ovarian hyperstimulation syndrome


Zahid Mohammed A Kadhim 
 Department of Physiology and Medical Physics, College of Medicine, University of Babylon, Hillah, Iraq

Correspondence Address:
Zahid Mohammed A Kadhim
Department of Physiology and Medical Physics, College of Medicine, University of Babylon, Hillah
Iraq

Background: Ovarian hyperstimulation syndrome (OHSS) is a life-threatening iatrogenic complication of ovarian stimulation during the assisted reproductive technique. Objective: This study was aimed to elucidate the effect of autonomic neuropathy on the occurrence of OHSS during assisted reproductive techniques. Materials and Methods: One hundred subfertile women underwent ovarian stimulation. The ovarian response was diagnosed by hormone concentrations and vaginal ultrasound. Autonomic function tests were done for all patients using Ewing's protocol. Results: Twenty-eight percent of subfertile women involved in this study had autonomic neuropathy. Out of 100 infertile women undergoing ovarian stimulation, only 5 (5%) had been developed OHSS, all of them had autonomic neuropathy (P < 0.05). The sensitivity and specificity of the autonomic neuropathy for the occurrence of OHSS was 100% and 58% which was insignificant (P > 0.05). The best cutoff score associated with OHSS was ≥1.5 which detected from receiver operating characteristic curve. The odds ratio for the absence of OHSS in patients without neuropathy was 9.891, which was significant as compared with the patients with neuropathy (P < 0.05). Conclusion: The study concludes that ovarian stimulation may cause autonomic function disturbance which can predict OHSS.


How to cite this article:
Kadhim ZA. The role of autonomic neuropathy in predicting ovarian hyperstimulation syndrome.Med J Babylon 2018;15:21-24


How to cite this URL:
Kadhim ZA. The role of autonomic neuropathy in predicting ovarian hyperstimulation syndrome. Med J Babylon [serial online] 2018 [cited 2020 Aug 14 ];15:21-24
Available from: http://www.medjbabylon.org/article.asp?issn=1812-156X;year=2018;volume=15;issue=1;spage=21;epage=24;aulast=Kadhim;type=0