• Users Online: 753
  • Print this page
  • Email this page
Year : 2020  |  Volume : 17  |  Issue : 4  |  Page : 358-362

High prevalence of vitamin D deficiency in patients with acute myocardial infarction: An Iraqi single-center study

1 Cardiac Catheterization Laboratory, Surgical Specialty Hospital - Cardiac Center, Erbil, Iraq
2 College of Health Sciences, Hawler Medical University, Erbil, Iraq
3 Cardiac Catheterization Laboratory, Surgical Specialty Hospital - Cardiac Center; Department of Surgery, College of Medicine, Hawler Medical University, Erbil, Iraq
4 Cardiac Surgery Department, Surgical Specialty Hospital - Cardiac Center, Erbil, Iraq
5 Erbil Directorates of Health, Erbil, Iraq

Correspondence Address:
Shwan Othman Amen
Surgical Specialty Hospital - Cardiac Center, Erbil
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/MJBL.MJBL_67_19

Get Permissions

Background: Coronary artery disease (CAD) is the leading cause of morbidity and mortality worldwide despite current advances in primary preventive and state-of-the art interventional strategies for effective CAD treatment. The major manifestation of CAD is the acute myocardial infarction (AMI). Vitamin D deficiency is associated with an increased risk of coronary atherosclerosis and AMI. Objectives: The major aim of this study was to determine the association of Vitamin D deficiency with AMI in Iraqi patients living in this region. Materials and Methods: Vitamin D level status was determined in 148 patients presented with AMI and 148 of healthy controls. Measurement of serum 25-hydroxyvitamin D (25(OH) D) levels was performed using enzymatic immunoassay method. Normal serum 25(OH) D level is = 30 ng/ml, while patients with level of 20–30 ng/ml was classified as insufficient, and those with level 10–20 ng/ml as deficient. The severe Vitamin D deficiency in patients was defined when serum 25(OH) D level was = 10 ng/ml. Results: The mean of 25(OH) D level was significantly lower in patients with AMI (8.73 ng/ml) as compared to healthy controls (13.60 ng/ml). Notably, the prevalence of severe deficiency of 25(OH) D level (<10 ng/ml) was higher in patients with AMI (67.6%) as compared to that in healthy controls (51.4%). This difference was statistically significant. Similar trend was observed for the prevalence of deficient Vitamin D level (≥10–<20 ng/ml) in cases (28.4%) as compared to control group (24.3%). Moreover, 4.1% of AMI patients showed insufficient 25(OH) D level in comparison to 13.5% in healthy individuals of control group. Interestingly there were no AMI patients with sufficient 25(OH) D level (30–100 ng/ml) while 10.8% of healthy individuals in the control group showed sufficient 25(OH) D level. Conclusions: This study concludes that Vitamin D deficiency is a highly prevalent condition in patients with AMI among Iraqi population and it is an emerging new risk factor associated with AMI.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded26    
    Comments [Add]    

Recommend this journal