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ORIGINAL ARTICLE
Year : 2021  |  Volume : 18  |  Issue : 2  |  Page : 80-82

Relationship between the ABO blood group and lung cancer susceptibility


Department of Medicine, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region, Iraq

Correspondence Address:
Zahir Salih Hussein
Department of Medicine, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region
Iraq
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/MJBL.MJBL_91_20

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Background: Lung cancer (LC) is one of the well-known fatal malignant neoplasms worldwide. Objective: The objective of this study was to determine the potential relationship between ABO and Rhesus blood groups with LC. Materials and Methods: A retrospective case series study was done on 500 patients diagnosed with LC using hospital case reports of both Nanakali Hospital and Rizgary Teaching Hospital and 182,408 healthy blood donors in Erbil city of Iraqi Kurdistan Region. Results: Blood groups of 500 LC patients were as follows: blood group A, 156 (31.2%); blood group B, 111 (22.2%); blood group O, 196 (39.2%); and blood group AB, 37 (7.4%), whereas blood groups of healthy donors were as follows: blood group A, 56,546 (31%); blood group B, 43,413 (23.8%); blood group O, 68,221 (37.4%); and blood group AB, 14,228 (7.8%). The difference was statistically not significant by Pearson's Chi-square (P = 0.909). Rh of patients was as follows: Rh negative in 42 patients (8.4%) and Rh positive in 458 patients (91.6%), whereas Rh of healthy donors was as follows: Rh negative in 18,241 patients (10%) and Rh positive in 164,167 patients (90%). The difference was statistically not significant by Pearson's Chi-square (P = 0.381). Conclusion: According to the results of the study, we found that there was no statistically significant relationship between ABO-Rhesus blood groups' LC susceptibility in general and also between different histopathological types.


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