Medical Journal of Babylon

REVIEW ARTICLE
Year
: 2021  |  Volume : 18  |  Issue : 1  |  Page : 1--5

Free radicals have an important role in cancer initiation and development


Shaimaa A Al-Oubaidy, Asmaa Mohammed Mekkey 
 Department of Histology and Human Anatomy, College of Medicine, University of Babylon, Hilla, Iraq

Correspondence Address:
Asmaa Mohammed Mekkey
Department of Histology and Human Anatomy, College of Medicine, University of Babylon, Hilla
Iraq

The present review deal with the role of free radicals in cancer initiation and development because of the importance of free radicals in signal cascade transition of the cells in addition to defense properties against inflammation, the negative function of free radicals when the cells unable to equilibrate the excessive production of free radical which lead to a harmful effect in cell components such as lipid peroxidation, protein structure alteration, and DNA mutation and structural modification of nucleic acid. This review deal with free radicals generation, function, and its role in different cancer stage starting with initiation, survival, development, proliferation, invasion, and angiogenesis, can be concluded the role of oxidative stress in our healthy life and use it as one of the cancer therapy strategies in the future.


How to cite this article:
Al-Oubaidy SA, Mekkey AM. Free radicals have an important role in cancer initiation and development.Med J Babylon 2021;18:1-5


How to cite this URL:
Al-Oubaidy SA, Mekkey AM. Free radicals have an important role in cancer initiation and development. Med J Babylon [serial online] 2021 [cited 2021 Aug 1 ];18:1-5
Available from: https://www.medjbabylon.org/article.asp?issn=1812-156X;year=2021;volume=18;issue=1;spage=1;epage=5;aulast=Al-Oubaidy;type=0