Medical Journal of Babylon

CASE REPORT
Year
: 2021  |  Volume : 18  |  Issue : 2  |  Page : 142--145

Mania with malignant catatonia due to nonparaneoplstic anti-n-methyl-d-aspartate receptors encephalitis in a 29-year-old female: A rare entity


Sunny Garg, Alka Chauhan 
 Department of Psychiatry, Bhagat Phool Singh Government Medical College for Women, Sonipat, Haryana, India

Correspondence Address:
Sunny Garg
Department of Psychiatry, Bhagat Phool Singh Government Medical College for Women, Khanpur Kalan, Sonipat - 131 305, Haryana
India

Anti-N-methyl-D-aspartate receptors (NMDARs) encephalitis is a rare neurological autoimmune encephalitis. Its symptoms may mimic psychosis as this disease is a neurological disorder in psychiatry costume. Disparity in clinical symptoms and nonsupportive laboratory investigations except the cerebrospinal fluid (CSF) analysis delays the diagnosis. We are presented with a case of 29-year-old female with psychiatric symptoms such as suspiciousness, decreased sleep, and boastfulness. Within a few days, the patient developed neurological symptoms such as seizures and disorientation, while the patient was on an antipsychotic along with benzodiazepines. Her symptoms worsened with autonomic instability, and the patient entered into catatonic phase of the illness. We reached a positive diagnosis of anti-NMDAR encephalitis through CSF analysis. The patient recovered completely with the help of immunotherapy and intensive cognitive rehabilitation. This case emphasizes the need of a multidisciplinary approach in the management, early detection, and adequate treatment of this challenging illness for better results for patients.


How to cite this article:
Garg S, Chauhan A. Mania with malignant catatonia due to nonparaneoplstic anti-n-methyl-d-aspartate receptors encephalitis in a 29-year-old female: A rare entity.Med J Babylon 2021;18:142-145


How to cite this URL:
Garg S, Chauhan A. Mania with malignant catatonia due to nonparaneoplstic anti-n-methyl-d-aspartate receptors encephalitis in a 29-year-old female: A rare entity. Med J Babylon [serial online] 2021 [cited 2022 Oct 7 ];18:142-145
Available from: https://www.medjbabylon.org/article.asp?issn=1812-156X;year=2021;volume=18;issue=2;spage=142;epage=145;aulast=Garg;type=0